Pakistan's foreign minister insisted on Sunday Washington and Tehran must uphold a ceasefire agreement, after marathon talks between the two sides to end the war in the Middle East ended without an agreement.

Iran's foreign ministry said no one had held any expectation that talks with the United States could have reached an agreement within one session after the negotiations in Islamabad stalled on Sunday.

Iran and the United States failed to reach an agreement to end the war in the Middle East, U.S. Vice President JD Vance said Sunday after marathon talks in Islamabad, adding that he was leaving after giving Tehran the "final and best offer".

Israeli Prime Minister Benjamin Netanyahu said on Saturday that the joint U.S.-Israeli campaign against Iran had succeeded in "crushing" the Islamic republic's nuclear and ballistic missile programs.

Two U.S. Navy warships transited the Strait of Hormuz to begin clearing Iranian-laid mines, U.S. Central Command said Saturday -- a claim Tehran denied as the Revolutionary Guards threatened to deal "severely" with military vessels crossing the strategic waterway.

U.S. President Donald Trump said prior to the failure of the Islamabad talks that he was not bothered about any outcome of the negotiations, insisting the United States had come out ahead from the war.

American and Iranian officials were holding face-to-face talks in Pakistan on Saturday, the most significant since the 1979 Islamic revolution as the foes try to end a war that plunged the Middle East into violence and rocked the world economy.

Ali Akbar Velayati, an adviser to Iran's supreme leader, said on X that Lebanese Prime Minister Nawaf Salam "should know that ignoring the unique role of the resistance and the heroic Hezbollah will expose Lebanon to irreparable security risks."

"Lebanon's stability rests exclusively on cohesion between the government and the resistance," he said.

The Lebanese National News Agency reported multiple Israeli strikes early Saturday in southern Lebanon, killing at least three people.

Hezbollah lawmaker Hassan Fadlallah on Saturday reiterated his group's rejection of direct negotiations between Israel and Lebanon, where authorities reported 10 people killed in Israeli attacks in the south.